Dexamethasone treatment for the acute respiratory distress syndrome: a multicentre, randomised controlled trial

  1. 1.

    • Villar J
    • Slutsky AS

    GOLDEN anniversary of the acute respiratory distress syndrome: still much work to do!.

    Curr Opin Crit Care.

    23

    :

    4-9

    View
    in Article

    • Scopus (24)
    • PubMed
    • Crossref
    • Google Scholar
  2. 2.

    • Brower RG
    • Matthay MA
    • Morris A
    • Schoenfeld D
    • Thompson BT
    • Wheeler A

    Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome.

    N Engl J Med.

    342

    :

    1301-1308

    View
    in Article

    • Scopus (10080)
    • PubMed
    • Crossref
    • Google Scholar
  3. 5.

    • Meduri GU
    • Headley AS
    • Golden E
    • et al.

    Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome: a randomized controlled trial.

    JAMA.

    280

    :

    159-165

    View
    in Article

    • Scopus (825)
    • PubMed
    • Crossref
    • Google Scholar
  4. 6.

    • Steinberg KP
    • Hudson LD
    • Goodman RB
    • et al.

    Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome.

    N Engl J Med.

    354

    :

    1671-1684

    View
    in Article

    • Scopus (1059)
    • PubMed
    • Crossref
    • Google Scholar
  5. 7.

    • Annane D
    • Sébille V
    • Bellissant E

    Effect of low doses of corticosteroids in septic shock patients with or without early acute respiratory distress syndrome.

    Crit Care Med.

    34

    :

    22-30

    View
    in Article

    • Scopus (229)
    • PubMed
    • Crossref
    • Google Scholar
  6. 9.

    • Annane D
    • Pastores SM
    • Rochwerg B
    • et al.

    Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part I): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.

    Crit Care Med.

    45

    :

    2078-2088

    View
    in Article

    • Scopus (145)
    • PubMed
    • Crossref
    • Google Scholar
  7. 11.

    • Bernard GR
    • Artigas A
    • Brigham KL
    • et al.

    The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination.

    Am J Respir Crit Care Med.

    149

    :

    818-824

    View
    in Article

    • Scopus (5298)
    • PubMed
    • Crossref
    • Google Scholar
  8. 13.

    • US Department of Health and Human Services from the Food and Drug Administration

    Enrichment strategies for clinical trials to support determination of effectiveness of human drugs and biological products. Guidance for industry.

    https://www.fda.gov/media/121320/download

    Date:

    March 2019

    Date accessed:

    May 8, 2019View
    in Article

    • Google Scholar
  9. 14.

    • Yehya N
    • Harhay MO
    • Curley MAQ
    • Schoenfeld DA
    • Reeder RW

    Re-appraisal of ventilator-free days in critical care research.

    Am J Respir Crit Care Med.

    200

    :

    828-836

    View
    in Article

    • Scopus (138)
    • PubMed
    • Crossref
    • Google Scholar
  10. 15.

    • Guérin C
    • Reignier J
    • Richard JC
    • et al.

    Prone positioning in severe acute respiratory distress syndrome.

    N Engl J Med.

    368

    :

    2159-2168

    View
    in Article

    • Scopus (2237)
    • PubMed
    • Crossref
    • Google Scholar
  11. 16.

    • The National Heart, Lung, and Blood Institute PETAL Clinical Trials Network

    Early neuromuscular blockade in the acute respiratory distress syndrome.

    N Engl J Med.

    380

    :

    1997-2008

    View
    in Article

    • Scopus (393)
    • PubMed
    • Crossref
    • Google Scholar
  12. 17.

    • Villar J
    • Belda J
    • Añón JM
    • et al.

    Evaluating the efficacy of dexamethasone in the treatment of patients with persistent acute respiratory distress syndrome: study protocol for a randomized controlled trial.

    Trials.

    17

    :

    342

    View
    in Article

    • Scopus (30)
    • PubMed
    • Crossref
    • Google Scholar
  13. 18.

    • Villar J
    • Pérez-Méndez L
    • López J
    • et al.

    An early PEEP/FIO2 trial identifies different degrees of lung injury in patients with acute respiratory distress syndrome.

    Am J Respir Crit Care Med.

    176

    :

    795-804

    View
    in Article

    • Scopus (240)
    • PubMed
    • Crossref
    • Google Scholar
  14. 20.

    • Azoulay É
    • Canet E
    • Raffoux E
    • et al.

    Dexamethasone in patients with acute lung injury from acute monocytic leukaemia.

    Eur Respir J.

    39

    :

    648-653

    View
    in Article

    • Scopus (59)
    • PubMed
    • Crossref
    • Google Scholar
  15. 21.

    • Papazian L
    • Doddoli C
    • Chetaille B
    • et al.

    A contributive result of open-lung biopsy improves survival in acute respiratory distress syndrome patients.

    Crit Care Med.

    35

    :

    755-762

    View
    in Article

    • Scopus (171)
    • PubMed
    • Crossref
    • Google Scholar
  16. 22.

    • Vincent JL
    • Moreno R
    • Takala J
    • et al.

    The SOFA (Sepsis-related Organ Failure Assessment) score to describe organ dysfunction/failure. On behalf of the working group on sepsis-related problems of the european society of intensive care medicine.

    Intensive Care Med.

    22

    :

    707-710

    View
    in Article

    • Scopus (7116)
    • PubMed
    • Crossref
    • Google Scholar
  17. 23.

    • Schoenfeld DA
    • Bernard GR

    Statistical evaluation of ventilator-free days as an efficacy measure in clinical trials of treatments for acute respiratory distress syndrome.

    Crit Care Med.

    30

    :

    1772-1777

    View
    in Article

    • Scopus (391)
    • PubMed
    • Crossref
    • Google Scholar
  18. 24.

    • Villar J
    • Blanco J
    • Añón JM
    • et al.

    The ALIEN study: incidence and outcome of acute respiratory distress syndrome in the era of lung protective ventilation.

    Intensive Care Med.

    37

    :

    1932-1941

    View
    in Article

    • Scopus (411)
    • PubMed
    • Crossref
    • Google Scholar
  19. 25.

    • Brun-Buisson C
    • Minelli C
    • Bertolini G
    • et al.

    Epidemiology and outcome of acute lung injury in European intensive care units. Results from the ALIVE study.

    Intensive Care Med.

    30

    :

    51-61

    View
    in Article

    • Scopus (543)
    • PubMed
    • Crossref
    • Google Scholar
  20. 26.

    • Talmor D
    • Sarge T
    • Malhotra A
    • et al.

    Mechanical ventilation guided by esophageal pressure in acute lung injury.

    N Engl J Med.

    359

    :

    2095-2104

    View
    in Article

    • Scopus (781)
    • PubMed
    • Crossref
    • Google Scholar
  21. 28.

    • Annane D
    • Pastores SM
    • Arlt W
    • et al.

    Critical illness-related corticosteroid insufficiency (CIRCI): a narrative review from a multispecialty task force of the society of critical care medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM).

    Crit Care Med.

    45

    :

    2089-2098

    View
    in Article

    • Scopus (35)
    • PubMed
    • Crossref
    • Google Scholar
  22. 30.

    • Gerard L
    • Bidoul T
    • Castanares-Zapatero D
    • et al.

    Open lung biopsy in nonresolving acute respiratory distress syndrome commonly identifies corticosteroid-sensitive pathologies, associated with better outcomes.

    Crit Care Med.

    46

    :

    907-914

    View
    in Article

    • Scopus (21)
    • PubMed
    • Crossref
    • Google Scholar
  23. 31.

    • Ashbaugh DG
    • Bigelow DB
    • Petty TL
    • Levine BE

    Acute respiratory distress in adults.

    Lancet.

    2

    :

    319-323

    View
    in Article

    • PubMed
    • Summary
    • Google Scholar
  24. 33.

    • Pastores SM
    • Annane D
    • Rochwerg B

    Guidelines for the diagnosis and management of critical illness-related corticosteroid insufficiency (CIRCI) in critically ill patients (Part II): Society of Critical Care Medicine (SCCM) and European Society of Intensive Care Medicine (ESICM) 2017.

    Intensive Care Med.

    44

    :

    474-477

    View
    in Article

    • Scopus (30)
    • PubMed
    • Crossref
    • Google Scholar
  25. 34.

    • Brouwer MC
    • McIntyre P
    • Prasad K
    • van de Beek D

    Corticosteroids for acute bacterial meningitis.

    Cochrane Database Syst Rev.

    6

    CD004405View
    in Article

    • PubMed
    • Google Scholar
  26. 35.

    • Meduri GU
    • Siemieniuk RAC
    • Ness RA
    • Seyler SJ

    Prolonged low-dose methylprednisolone treatment is highly effective in reducing duration of mechanical ventilation and mortality in patients with ARDS.

    J Intensive Care.

    6

    :

    53

    View
    in Article

    • Scopus (64)
    • PubMed
    • Crossref
    • Google Scholar
  27. 36.

    • Maerz LL
    • Akhtar S

    Perioperative glycemic management in 2011: paradigm shifts.

    Curr Opin Crit Care.

    17

    :

    370-375

    View
    in Article

    • PubMed
    • Google Scholar
  28. 38.

    • Burnham EL
    • Janssen WJ
    • Riches DW
    • Moss M
    • Downey GP

    The fibroproliferative response in acute respiratory distress syndrome: mechanisms and clinical significance.

    Eur Respir J.

    43

    :

    276-285

    View
    in Article

    • Scopus (200)
    • PubMed
    • Crossref
    • Google Scholar
  29. 39.

    • Bernard GR
    • Vincent JL
    • Laterre PF
    • et al.

    Efficacy and safety of recombinant human activated protein C for severe sepsis.

    N Engl J Med.

    344

    :

    699-709

    View
    in Article

    • Scopus (5053)
    • PubMed
    • Crossref
    • Google Scholar
  30. 40.

    • McKeever T
    • Mortimer K
    • Wilson A
    • et al.

    Quadrupling inhaled glucocorticoid dose to abort asthma exacerbations.

    N Engl J Med.

    378

    :

    902-910

    View
    in Article

    • Scopus (102)
    • PubMed
    • Crossref
    • Google Scholar
  31. 41.

    • Zeuzem S
    • Dusheiko GM
    • Salupere R
    • et al.

    Sofosbuvir and ribavirin in HCV genotypes 2 and 3.

    N Engl J Med.

    370

    :

    1993-2001

    View
    in Article

    • Scopus (680)
    • PubMed
    • Crossref
    • Google Scholar
  32. 42.

    • Ryan CJ
    • Smith MR
    • de Bono JS
    • et al.

    Abiraterone in metastatic prostate cancer without previous chemotherapy.

    N Engl J Med.

    368

    :

    138-148

    View
    in Article

    • Scopus (2145)
    • PubMed
    • Crossref
    • Google Scholar
  33. 44.

    • Combes A
    • Hajage D
    • Capellier G
    • et al.

    Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome.

    N Engl J Med.

    378

    :

    1965-1975

    View
    in Article

    • Scopus (1088)
    • PubMed
    • Crossref
    • Google Scholar
  34. 45.

    • Girardis M
    • Busani S
    • Damiani E
    • et al.

    Effect of conservative vs. conventional oxygen therapy on mortality among patients in an intensive care unit. The oxygen-ICU randomized clinical trial.

    JAMA.

    316

    :

    1583-1589

    View
    in Article

    • Scopus (411)
    • PubMed
    • Crossref
    • Google Scholar
  35. 46.

    • National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome (ARDS) Clinical Trials Network

    Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial.

    JAMA.

    307

    :

    795-803

    View
    in Article

    • Scopus (654)
    • PubMed
    • Crossref
    • Google Scholar
  36. 47.

    • Hébert PC
    • Wells G
    • Blajchman MA
    • et al.

    A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care.

    N Engl J Med.

    340

    :

    409-417

    View
    in Article

    • Scopus (4043)
    • PubMed
    • Crossref
    • Google Scholar